Abstract
Coatomer is a multisubunit complex involved in trafficking of vesicles between the endoplasmatic reticulum and the Golgi apparatus. From sequence homologies, all seven subunits, α-, β-, β′-, γ-, δ-, ε-, and ζ-COP, are encoded in the genome of Trypanosoma brucei. The complete predicted amino-acid sequences of β-, β′-, and ζ-COP show only 20-30% identity with higher eucaryotic homologues. The trypanosome coatomer complex was partially purified using a procedure similar to that used for bovine coatomer.
| Original language | English |
|---|---|
| Pages (from-to) | 55-61 |
| Number of pages | 7 |
| Journal | Molecular and Biochemical Parasitology |
| Volume | 115 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2001 |
| Externally published | Yes |
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