The course of cognitive functioning over six months in individuals at clinical high risk for psychosis

Mariapaola Barbato; Mark A Colijn; Richard  Keefe; Diana O Perkins; Scott W Woods; Keith A Hawkins; Bruce Christensen; Jean Margaret Addington

doi:10.1016/j.psychres.2012.10.013

The course of cognitive functioning over six months in individuals at clinical high risk for psychosis

Mariapaola Barbato, Mark A Colijn, Richard Keefe, Diana O Perkins, Scott W Woods, Keith A Hawkins, Bruce Christensen, Jean Margaret Addington

Research output: Contribution to journal › Article › peer-review

Abstract

Cognitive impairment is common in psychosis and has recently been observed in individuals at clinical high risk (CHR) of developing psychosis. The purpose of this study was to characterize longitudinal change in cognition among CHR individuals, and compare cognition of CHR individuals who later convert to psychosis to that of CHR who do not convert. Participants were tested at baseline and followed-up after six months using a comprehensive cognitive test battery. Individuals who did not convert to psychosis either remained stable or significantly improved in their cognitive performance. At baseline participants who converted to psychosis compared to non-converters exhibited poorer performance in several cognitive tests, suggesting that some cognitive impairment is already present before conversion. Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis. Â© 2012 Elsevier Ireland Ltd. All rights reserved

Original language	English
Pages (from-to)	195-199
Journal	Psychiatry Research
Volume	206
Issue number	2-Mar
DOIs	https://doi.org/10.1016/j.psychres.2012.10.013
Publication status	Published - 2013

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10.1016/j.psychres.2012.10.013

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title = "The course of cognitive functioning over six months in individuals at clinical high risk for psychosis",

abstract = "Cognitive impairment is common in psychosis and has recently been observed in individuals at clinical high risk (CHR) of developing psychosis. The purpose of this study was to characterize longitudinal change in cognition among CHR individuals, and compare cognition of CHR individuals who later convert to psychosis to that of CHR who do not convert. Participants were tested at baseline and followed-up after six months using a comprehensive cognitive test battery. Individuals who did not convert to psychosis either remained stable or significantly improved in their cognitive performance. At baseline participants who converted to psychosis compared to non-converters exhibited poorer performance in several cognitive tests, suggesting that some cognitive impairment is already present before conversion. Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis. {\^A}{\textcopyright} 2012 Elsevier Ireland Ltd. All rights reserved",

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AU - Barbato, Mariapaola

AU - Colijn, Mark A

AU - Keefe, Richard

AU - Perkins, Diana O

AU - Woods, Scott W

AU - Hawkins, Keith A

AU - Christensen, Bruce

AU - Addington, Jean Margaret

PY - 2013

Y1 - 2013

N2 - Cognitive impairment is common in psychosis and has recently been observed in individuals at clinical high risk (CHR) of developing psychosis. The purpose of this study was to characterize longitudinal change in cognition among CHR individuals, and compare cognition of CHR individuals who later convert to psychosis to that of CHR who do not convert. Participants were tested at baseline and followed-up after six months using a comprehensive cognitive test battery. Individuals who did not convert to psychosis either remained stable or significantly improved in their cognitive performance. At baseline participants who converted to psychosis compared to non-converters exhibited poorer performance in several cognitive tests, suggesting that some cognitive impairment is already present before conversion. Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis. Â© 2012 Elsevier Ireland Ltd. All rights reserved

AB - Cognitive impairment is common in psychosis and has recently been observed in individuals at clinical high risk (CHR) of developing psychosis. The purpose of this study was to characterize longitudinal change in cognition among CHR individuals, and compare cognition of CHR individuals who later convert to psychosis to that of CHR who do not convert. Participants were tested at baseline and followed-up after six months using a comprehensive cognitive test battery. Individuals who did not convert to psychosis either remained stable or significantly improved in their cognitive performance. At baseline participants who converted to psychosis compared to non-converters exhibited poorer performance in several cognitive tests, suggesting that some cognitive impairment is already present before conversion. Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis. Â© 2012 Elsevier Ireland Ltd. All rights reserved

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DO - 10.1016/j.psychres.2012.10.013

M3 - Article

VL - 206

SP - 195

EP - 199

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2-Mar

ER -

The course of cognitive functioning over six months in individuals at clinical high risk for psychosis

Abstract

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