Abstract
The sharpless asymmetric aminohydroxylation (AA) reaction was discussed. The reaction employed a catalyst consisting of cinchona alkaloid derived ligand and an osmium species in combination with a stoichiometric nitrogen source. The ligand increased the rate of the reaction, influenced regioselectivity and induced enantioselectivity in the AA reactions. The three nitrogen sources used in the reaction were sulfonamides, carbamates and amides.
| Original language | English |
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| Pages (from-to) | 2733-2746 |
| Number of pages | 14 |
| Journal | Journal of the Chemical Society, Perkin Transactions 1 |
| Volume | 24 |
| DOIs | |
| Publication status | Published - 21 Dec 2002 |
| Externally published | Yes |