The structures of three new Galbulimima alkaloids

Lewis N. Mander; Anthony C. Willis; Anthony J. Herlt; Walter C. Taylor

doi:10.1016/j.tetlet.2009.10.019

The structures of three new Galbulimima alkaloids

Lewis N. Mander^*, Anthony C. Willis, Anthony J. Herlt, Walter C. Taylor

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The structures of three new alkaloids isolated from the bark of the rain forest tree Galbulimima belgraveana, have been determined by a combination of NMR spectroscopy and X-ray crystallography. One of the alkaloids, himgrine (5), was shown to be an oxygenated derivative of himbacine (1), while the second, GB16, (8) proved to be identical with a degradation product from himgaline (4). The remaining alkaloid, GB17 (12) possesses an entirely new and unexpected skeleton.

Original language	English
Pages (from-to)	7089-7092
Number of pages	4
Journal	Tetrahedron Letters
Volume	50
Issue number	50
DOIs	https://doi.org/10.1016/j.tetlet.2009.10.019
Publication status	Published - 16 Dec 2009

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10.1016/j.tetlet.2009.10.019

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AB - The structures of three new alkaloids isolated from the bark of the rain forest tree Galbulimima belgraveana, have been determined by a combination of NMR spectroscopy and X-ray crystallography. One of the alkaloids, himgrine (5), was shown to be an oxygenated derivative of himbacine (1), while the second, GB16, (8) proved to be identical with a degradation product from himgaline (4). The remaining alkaloid, GB17 (12) possesses an entirely new and unexpected skeleton.

KW - Alkaloids

KW - Biosynthesis

KW - Galbulimima belgraveana

KW - Novel structures

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DO - 10.1016/j.tetlet.2009.10.019

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 50

ER -

The structures of three new Galbulimima alkaloids

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