Abstract
Compound ent-1 as well as certain related homochiral and polyfunctionalized cyclohexenes have been prepared from the 1,2-diacetal 4 that is itself readily derived from L-tartaric acid (3). Grignard addition and ring-closing metathesis processes constitute the key steps associated with the reaction sequences involved. This work provides a method for obtaining a range of potentially useful cyclohexenone-containing chirons that are enantiomerically related to those that have been prepared from the homochiral cis-1,2-dihydrocatechol 2, the product of the microbial biotransformation of bromobenzene.
Original language | English |
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Pages (from-to) | 290-303 |
Number of pages | 14 |
Journal | Heterocycles |
Volume | 95 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2017 |