The use of hypertonic solutions in sepsis

Frank M.P. Van Haren

doi:10.1016/j.tacc.2012.10.001

The use of hypertonic solutions in sepsis

Frank M.P. Van Haren^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Fluid therapy is a key component in the treatment of patients with septic shock. Recent data suggests that hypertonic fluid administration in sepsis may have beneficial effects on the global circulation and the cardiac function that exceed simple intravascular volume expansion. In addition, hypertonic resuscitation may exert specific effects on inflammatory pathways and endothelial function.This review summarizes the current knowledge on this topic and highlights the need for further research to translate some of the promising observations into relevant patient centred outcomes.

Original language	English
Pages (from-to)	37-41
Number of pages	5
Journal	Trends in Anaesthesia and Critical Care
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/j.tacc.2012.10.001
Publication status	Published - Feb 2013

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10.1016/j.tacc.2012.10.001

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abstract = "Fluid therapy is a key component in the treatment of patients with septic shock. Recent data suggests that hypertonic fluid administration in sepsis may have beneficial effects on the global circulation and the cardiac function that exceed simple intravascular volume expansion. In addition, hypertonic resuscitation may exert specific effects on inflammatory pathways and endothelial function.This review summarizes the current knowledge on this topic and highlights the need for further research to translate some of the promising observations into relevant patient centred outcomes.",

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KW - Sepsis

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The use of hypertonic solutions in sepsis

Abstract

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