Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

Martin G. Banwell*, Alison J. Edwards, Katrina A. Jolliffe, Jason A. Smith, Ernest Hamel, Pascal Verdier-Pinard

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    71 Citations (Scopus)

    Abstract

    The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.

    Original languageEnglish
    Pages (from-to)296-305
    Number of pages10
    JournalOrganic and Biomolecular Chemistry
    Volume1
    Issue number2
    DOIs
    Publication statusPublished - 21 Jan 2003

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