Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

Martin G. Banwell; Alison J. Edwards; Katrina A. Jolliffe; Jason A. Smith; Ernest Hamel; Pascal Verdier-Pinard

doi:10.1039/b209992f

Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

Martin G. Banwell^*, Alison J. Edwards, Katrina A. Jolliffe, Jason A. Smith, Ernest Hamel, Pascal Verdier-Pinard

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

Abstract

The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.

Original language	English
Pages (from-to)	296-305
Number of pages	10
Journal	Organic and Biomolecular Chemistry
Volume	1
Issue number	2
DOIs	https://doi.org/10.1039/b209992f
Publication status	Published - 21 Jan 2003

Access to Document

10.1039/b209992f

Cite this

@article{540acb69fdcf4c17b321b6ddc28faf42,

title = "Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi",

abstract = "The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.",

author = "Banwell, \{Martin G.\} and Edwards, \{Alison J.\} and Jolliffe, \{Katrina A.\} and Smith, \{Jason A.\} and Ernest Hamel and Pascal Verdier-Pinard",

year = "2003",

month = jan,

day = "21",

doi = "10.1039/b209992f",

language = "English",

volume = "1",

pages = "296--305",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "2",

}

TY - JOUR

T1 - Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

AU - Banwell, Martin G.

AU - Edwards, Alison J.

AU - Jolliffe, Katrina A.

AU - Smith, Jason A.

AU - Hamel, Ernest

AU - Verdier-Pinard, Pascal

PY - 2003/1/21

Y1 - 2003/1/21

N2 - The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.

AB - The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.

UR - https://www.scopus.com/pages/publications/0037601344

U2 - 10.1039/b209992f

DO - 10.1039/b209992f

M3 - Article

SN - 1477-0520

VL - 1

SP - 296

EP - 305

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 2

ER -

Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

Abstract

Access to Document

Other files and links

Fingerprint

Cite this