TY - JOUR
T1 - Type 2 diabetes after a pregnancy with gestational diabetes among first nations women in Australia
T2 - The PANDORA study
AU - Wood, Anna J.
AU - Boyle, Jacqueline A.
AU - Barr, Elizabeth L.M.
AU - Barzi, Federica
AU - Hare, Matthew J.L.
AU - Titmuss, Angela
AU - Longmore, Danielle K.
AU - Death, Elizabeth
AU - Kelaart, Joanna
AU - Kirkwood, Marie
AU - Graham, Sian
AU - Connors, Christine
AU - Moore, Elizabeth
AU - O'Dea, Kerin
AU - Oats, Jeremy J.N.
AU - McIntyre, Harold D.
AU - Zimmet, Paul Z.
AU - Lu, Zhong X.
AU - Brown, Alex
AU - Shaw, Jonathan E.
AU - Maple-Brown, Louise J.
N1 - Publisher Copyright:
© 2021 The Author(s)
PY - 2021/11
Y1 - 2021/11
N2 - Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.
AB - Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.
KW - Diabetes in pregnancy
KW - Gestational diabetes
KW - Indigenous health
UR - http://www.scopus.com/inward/record.url?scp=85118188614&partnerID=8YFLogxK
U2 - 10.1016/j.diabres.2021.109092
DO - 10.1016/j.diabres.2021.109092
M3 - Article
SN - 0168-8227
VL - 181
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
M1 - 109092
ER -