Type i Interferon Keeps IL-1β in Check

Si Ming Man, Thirumala Devi Kanneganti*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

1 Citation (Scopus)


Type I interferons have diametric roles in the host defense against pathogens. In this issue of Cell Host & Microbe, Castiglia et al. (2016) demonstrate that type I interferons produced during Streptococcus pyogenes infection are required to prevent inflammation-associated tissue damage and host lethality driven by the pro-inflammatory cytokine IL-1β.

Original languageEnglish
Pages (from-to)272-274
Number of pages3
JournalCell Host and Microbe
Issue number3
Publication statusPublished - 9 Mar 2016
Externally publishedYes


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