Type i Interferon Keeps IL-1β in Check

Si Ming Man; Thirumala Devi Kanneganti

doi:10.1016/j.chom.2016.02.015

Type i Interferon Keeps IL-1β in Check

Si Ming Man, Thirumala Devi Kanneganti^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

1 Citation (Scopus)

Abstract

Type I interferons have diametric roles in the host defense against pathogens. In this issue of Cell Host & Microbe, Castiglia et al. (2016) demonstrate that type I interferons produced during Streptococcus pyogenes infection are required to prevent inflammation-associated tissue damage and host lethality driven by the pro-inflammatory cytokine IL-1β.

Original language	English
Pages (from-to)	272-274
Number of pages	3
Journal	Cell Host and Microbe
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/j.chom.2016.02.015
Publication status	Published - 9 Mar 2016
Externally published	Yes

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10.1016/j.chom.2016.02.015

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title = "Type i Interferon Keeps IL-1β in Check",

abstract = "Type I interferons have diametric roles in the host defense against pathogens. In this issue of Cell Host & Microbe, Castiglia et al. (2016) demonstrate that type I interferons produced during Streptococcus pyogenes infection are required to prevent inflammation-associated tissue damage and host lethality driven by the pro-inflammatory cytokine IL-1β.",

author = "Man, {Si Ming} and Kanneganti, {Thirumala Devi}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

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day = "9",

doi = "10.1016/j.chom.2016.02.015",

language = "English",

volume = "19",

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T1 - Type i Interferon Keeps IL-1β in Check

AU - Man, Si Ming

AU - Kanneganti, Thirumala Devi

PY - 2016/3/9

Y1 - 2016/3/9

N2 - Type I interferons have diametric roles in the host defense against pathogens. In this issue of Cell Host & Microbe, Castiglia et al. (2016) demonstrate that type I interferons produced during Streptococcus pyogenes infection are required to prevent inflammation-associated tissue damage and host lethality driven by the pro-inflammatory cytokine IL-1β.

AB - Type I interferons have diametric roles in the host defense against pathogens. In this issue of Cell Host & Microbe, Castiglia et al. (2016) demonstrate that type I interferons produced during Streptococcus pyogenes infection are required to prevent inflammation-associated tissue damage and host lethality driven by the pro-inflammatory cytokine IL-1β.

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U2 - 10.1016/j.chom.2016.02.015

DO - 10.1016/j.chom.2016.02.015

M3 - Short survey

SN - 1931-3128

VL - 19

SP - 272

EP - 274

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 3

ER -

Type i Interferon Keeps IL-1β in Check

Abstract

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