Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

Rajiv Kumar; Patrick T Bunn; Siddharth Sankar Singh; Susanna S Ng; Marcela Montes de Oca; Fabian de Labastida Rivera; Shashi Bhushan  Chauhan; Neetu Singh; Rebecca J Faleiro; Chelsea L Edwards; Meru Sheel

doi:10.1016/j.celrep.2020.01.099.

Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

Rajiv Kumar, Patrick T Bunn, Siddharth Sankar Singh, Susanna S Ng, Marcela Montes de Oca, Fabian de Labastida Rivera, Shashi Bhushan Chauhan, Neetu Singh, Rebecca J Faleiro, Chelsea L Edwards, Meru Sheel

Research output: Contribution to journal › Article › peer-review

Abstract

Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases.

Original language	English
Pages (from-to)	2512-2525
Journal	Cell Reports
Volume	30
DOIs	https://doi.org/10.1016/j.celrep.2020.01.099.
Publication status	Published - 2020

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10.1016/j.celrep.2020.01.099.

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@article{cb982ae119af4ebca17f2858042c5268,

title = "Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis",

abstract = "Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases.",

author = "Rajiv Kumar and Bunn, {Patrick T} and Singh, {Siddharth Sankar} and Ng, {Susanna S} and {de Oca}, {Marcela Montes} and {de Labastida Rivera}, Fabian and Chauhan, {Shashi Bhushan} and Neetu Singh and Faleiro, {Rebecca J} and Edwards, {Chelsea L} and Meru Sheel",

year = "2020",

doi = "10.1016/j.celrep.2020.01.099.",

language = "English",

volume = "30",

pages = "2512--2525",

journal = "Cell Reports",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

AU - Kumar, Rajiv

AU - Bunn, Patrick T

AU - Singh, Siddharth Sankar

AU - Ng, Susanna S

AU - de Oca, Marcela Montes

AU - de Labastida Rivera, Fabian

AU - Chauhan, Shashi Bhushan

AU - Singh, Neetu

AU - Faleiro, Rebecca J

AU - Edwards, Chelsea L

AU - Sheel, Meru

PY - 2020

Y1 - 2020

N2 - Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases.

AB - Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases.

U2 - 10.1016/j.celrep.2020.01.099.

DO - 10.1016/j.celrep.2020.01.099.

M3 - Article

VL - 30

SP - 2512

EP - 2525

JO - Cell Reports

JF - Cell Reports

ER -

Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

Abstract

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