Vitamin D status during pregnancy and aspects of offspring health

Anne Louise Ponsonby*, Robyn M. Lucas, Sharon Lewis, Jane Halliday

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    77 Citations (Scopus)

    Abstract

    Low maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known.

    Original languageEnglish
    Pages (from-to)389-407
    Number of pages19
    JournalNutrients
    Volume2
    Issue number3
    DOIs
    Publication statusPublished - Mar 2010

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