Wide genome comparisons reveal the origins of the human X chromosome

Matthias Kohn; Hildegard Kehrer-Sawatzki; Walther Vogel; Jennifer A.M. Graves; Horst Hameister

doi:10.1016/j.tig.2004.09.008

Wide genome comparisons reveal the origins of the human X chromosome

Matthias Kohn, Hildegard Kehrer-Sawatzki, Walther Vogel, Jennifer A.M. Graves, Horst Hameister

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

Abstract

The eutherian X chromosome has one of the most conserved gene arrangements in mammals. Although earlier comparisons with distantly related mammalian groups pointed towards separate origins for the short and long arms, much deeper comparisons are now possible using draft sequences of the chicken genome, in combination with genome sequences from pufferfish and zebrafish. This enables surprising new insights into the origins of the mammalian X chromosome.

Original language	English
Pages (from-to)	598-603
Number of pages	6
Journal	Trends in Genetics
Volume	20
Issue number	12
DOIs	https://doi.org/10.1016/j.tig.2004.09.008
Publication status	Published - Dec 2004

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10.1016/j.tig.2004.09.008

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title = "Wide genome comparisons reveal the origins of the human X chromosome",

abstract = "The eutherian X chromosome has one of the most conserved gene arrangements in mammals. Although earlier comparisons with distantly related mammalian groups pointed towards separate origins for the short and long arms, much deeper comparisons are now possible using draft sequences of the chicken genome, in combination with genome sequences from pufferfish and zebrafish. This enables surprising new insights into the origins of the mammalian X chromosome.",

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AU - Hameister, Horst

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JO - Trends in Genetics

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Wide genome comparisons reveal the origins of the human X chromosome

Abstract

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